Darren M Brenner, MD Disclosures: Advisor and Consultant-Current-Ironwood, Allergan (Abbvie), Salix, Takeda, Bausch, Arena, Alphasigma, Alnylam Pharmaceuticals|Speakers Bureau-Current-Ironwood, Allergan (Abbive), Salix, Takeda Pharmaceuticals|Associate Editor-American Journal of Gastroenterology, GI Health Foundation, Pri-Med No Bio Available.